Superfamilie

Superfamilie Kategorien

Superfamilie steht für: Makrofamilie, auch Superfamilie, Zusammenfassung von Sprachfamilien in der Sprachwissenschaft; Überfamilie, auch Superfamilie. SUPERFAMILY – HMM-Bibliothek zur Darstellung von Superfamilien und Datenbank von Superfamilien- und Familien-Annotierungen aller bisher komplett​. Immunglobulin-Superfamilie. Englisch: immunoglobulin superfamily. 1 Definition. Als Immunglobulin-Superfamilie, kurz IgSF, bezeichnet. Immunglobulingen-Superfamilie, Ig-Superfamilie, Abk. IgSF, E immunoglobulin gene superfamily, Familie von Proteinen, die eine oder mehrere. Immunglobulin-Superfamilie, Ig-Superfamilie, Familie von Proteinen, die eine oder mehrere Immunglobulin-Domänen aufweisen (vgl. Abb.). Diese Dom&#.

Superfamilie

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Main article: sequence homology. Main article: structural alignment. Main article: enzyme mechanism. Nucleic Acids Research.

The Biochemical Journal. Archived from the original on 24 October Retrieved 8 December Nature Reviews Molecular Cell Biology. Annual Review of Biochemistry.

Molecular Biology and Evolution. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature". The Journal of Biological Chemistry.

Molecular Biology Reports. Current Opinion in Structural Biology. Nature Reviews. Journal of Molecular Biology.

Archives of Biochemistry and Biophysics. Genome Research. Journal of Molecular Evolution. Protein and Peptide Letters. Archived from the original on 29 July Retrieved 28 May Introduction to protein structure 2nd ed.

New York: Garland Pub. Crystallographic analysis at 1. Structural classification, sequence patterns and common core".

Protein Profile. Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator. EC number Enzyme superfamily Enzyme family List of enzymes.

Categories : Molecular evolution Protein families Protein folds Protein classification Protein superfamilies. Hidden categories: Commons category link is on Wikidata.

Namespaces Article Talk. Views Read Edit View history. Help Community portal Recent changes Upload file. Download as PDF Printable version.

Superfamilie Video

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Sign up or log in Sign up using Google. Sign up using Facebook. Sign up using Email and Password. Post as a guest Name. They are therefore amongst the most ancient evolutionary events currently studied.

Some superfamilies have members present in all kingdoms of life , indicating that the last common ancestor of that superfamily was in the last universal common ancestor of all life LUCA.

Superfamily members may be in different species, with the ancestral protein being the form of the protein that existed in the ancestral species orthology.

Conversely, the proteins may be in the same species, but evolved from a single protein whose gene was duplicated in the genome paralogy. A majority of proteins contain multiple domains.

Additionally, the number of domain combinations seen in nature is small compared to the number of possibilities, suggesting that selection acts on all combinations.

Globin superfamily - Members share an 8- alpha helix globular globin fold. The clan contains both cysteine and serine proteases different nucleophiles.

Serpin superfamily - Members share a high-energy, stressed fold which can undergo a large conformational change , which is typically used to inhibit serine and cysteine proteases by disrupting their structure.

It is one of the most common protein folds and the monophylicity of this superfamily is still contested. Several biological databases document protein superfamilies and protein folds, for example:.

Similarly there are algorithms that search the PDB for proteins with structural homology to a target structure, for example:.

From Wikipedia, the free encyclopedia. Main article: sequence homology. Main article: structural alignment. Main article: enzyme mechanism.

Nucleic Acids Research. The Biochemical Journal. Archived from the original on 24 October Retrieved 8 December Nature Reviews Molecular Cell Biology.

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